Integration of Individual Residential Histories into Cancer Research (R21) PA-17-295 and (R01) PA-17-298




Standard R01 dates apply

Standard R21 dates apply


The purpose of this Funding Opportunity Announcement (FOA) is to support substantive investigation of the role of individual residential histories in cancer etiology and outcomes, and to encourage the development of complex analytical strategies in support of substantive investigation.

There is a growing recognition of the importance of residential histories – a record of an individual’s places of residence across his or her lifetime — in cancer research, as part of evolving cancer data ecosystem.  Residential history encapsulates a person’s multiple interactions with the social and physical environment that can result in lasting health impact and is an important factor in assessing the effects of exposures on disease onset, as demonstrated in focused studies.  Lifetime residential history records can reveal the variety of potential and actual exposures throughout person’s life including, but not limited to: neighborhood characteristics, physical conditions of housing, tobacco and alcohol consumption, food environments, chemical exposures to contaminants in water, soil, and air, accessibility to healthcare resources, and health disparities.

This FOA is expected to engage scientists from a range of disciplines, including epidemiology, statistics, geospatial science, computer science, demography, decision science, and behavioral science, to effectively integrate individual residential histories into cancer research.

Geospatial expertise is essential for generating new knowledge about the residential context relative to cancer risk, etiology, prevention, treatment, and outcomes. Computer science and informatics are crucial for the development of methodology that would ensure more precise matching of residential information and location (geocoding), improve linkage to automated data sources, and generate reliable lifetime residential histories. Cancer surveillance science, in conjunction with statistical, epidemiological, and medical expertise, is extremely important in answering substantial questions related to the use of lifetime residential histories in the analysis of cancer risk and cancer burden.

In addition, a combination of scientific expertise in demography and behavioral science in addressing the role of lifetime residential histories in the context of cancer can help facilitate more precise assessment of cancer disparities.



Available Funding:

R01: Application budgets are not limited but need to reflect the actual needs of the proposed project. The maximum project period is 5 years.

R21: The combined budget for direct costs for the two-year project period may not exceed $275,000. No more than $200,000 may be requested in a single year. The maximum project period is 2 years.

Link to Full RFP: