Department of Defense
Pre-Application Submission Deadline: 5:00 p.m. Eastern time (ET), November 9, 2016
Application Submission Deadline: 11:59 p.m. ET, November 30, 2016
The PRP (formerly the Neurotoxin Exposure Treatment Parkinson’s Research Program) was initiated in FY97 to provide support for research of exceptional scientific merit leading to an understanding of the cause, prevention, and treatment of the loss of dopaminergic neurons in the substantia nigra that results in Parkinson’s disease. Appropriations for the PRP from FY97 through FY15 totaled $388.75 million (M). The FY16 appropriation is $16M. The PRP challenges the scientific community to develop the most impactful research that will advance the understanding of and ultimately end Parkinson’s disease. The vision of the PRP is to slow the progression of, prevent, and cure Parkinson’s disease in order to lessen personal and societal impact of the disorder.
All applications to the FY16 PRP Focused Idea Award Program Announcement/Funding Opportunity MUST address at least one of the following FY16 PRP Focused Idea Award Focus Areas:
- Studies of the neurovascular unit (including neurons, glia, the microvasculature, and the blood-brain barrier) in Parkinson’s disease and changes associated with its treatment.
- Identification and evaluation of mechanisms in early Parkinson’s disease involving olfactory, microbiome, gastrointestinal, and/or autonomic nervous systems.
- Mechanisms of neuroplasticity and compensation in Parkinson’s disease, such as influences of sleep, exercise, and diet.
The FY16 PRP Focused Idea Award seeks applications from investigators from a spectrum of disciplines including, but not limited to, basic science, engineering, bioinformatics, population science, translational research, and clinical research. The application should demonstrate that the research team’s background is appropriate to successfully achieve the proposed research and contribute to the field of Parkinson’s disease research.
Independent investigators at or above the level of Assistant Professor (or equivalent) are eligible to submit an application.
Cost sharing/matching is not an eligibility requirement.
Eligible investigators must apply through an organization. Organizations eligible to apply include Federal agencies, national, international, for-profit, nonprofit, public, and private organizations. DoD FY16 Parkinson’s Research Program Focused Idea Award 6
An intramural investigator is defined as a DoD military or civilian employee working within a DoD laboratory or medical treatment facility, or working in a DoD activity embedded within a civilian medical center. Submissions from intramural (DoD) organizations are allowed and encouraged for this Program Announcement/Funding Opportunity. Applicants submitting through their intramural organizations are reminded to coordinate receipt and commitment of funds through their respective resource managers. If an investigator at an intramural organization is named as a collaborator on an application submitted through an extramural organization, the application must include a letter from the collaborator’s Commander or Commanding Officer at the intramural organization that authorizes the collaborator’s involvement.
The maximum period of performance is 3 years.
The anticipated direct costs budgeted for the entire period of performance will not exceed $350,000. Indirect costs are to be budgeted in accordance with the organization’s negotiated rate. No budget will be approved by the Government exceeding $350,000 direct costs or using an indirect rate exceeding the organization’s negotiated rate.
All direct and indirect costs of any subaward (subgrant or subcontract) must be included in the total direct costs of the primary award.
The applicant may request the entire maximum funding amount for a project that may have a period of performance less than the maximum 3 years.
The CDMRP expects to allot approximately $3.36M of the $16M FY16 appropriation(s) to fund approximately six Focused Idea Award applications, depending on the quality and number of applications received. Funding of applications received in response to this Program Announcement/Funding Opportunity is contingent upon the availability of Federal funds for this program.
Link to Full RFP: